Welcome to the Kim laboratory!
We wish to understand how DNA repair system preserves genome stability and how its deregulation leads to human pathological conditions, especially cancer. We believe that elucidating basic mechanisms of how organisms sense and repair damaged DNA will ultimately help us design novel therapeutics to treat cancer.
In particular, we focus on:
1. exploring signaling of the DNA replication stress response and replication-associated DNA repair
2. elucidating cross-talks between DNA repair and cellular
signalling regulated by oncogenes and tumor suppressors
3. developing anti-cancer therapeutics by exploiting DNA repair
pathways deregulated in cancer